INTERNATIONAL IMMUNOPHARMACOLOGY

Published by Elsevier Science. ISSN: 1567-5769.Merger of International Journal of Immunopharmacology and Immunopharmacology. International Immunopharmacology is the primary vehicle for the publication of original research papers pertinent to the overlapping areas of immunology, pharmacology, cytokine biology, immunotherapy, immunopathology and immunotoxicology. Review articles that encompass these subjects are also welcome. The subject material appropriate for submission includes: Clinical studies employing immunotherapy of any type including the use of: bacterial and chemical agents; thymic hormones, interferon, lymphokines, etc., in transplantation and diseases such as cancer, immunodeficiency, chronic infection and allergic, inflammatory or autoimmune disorders. Studies on the mechanisms of action of these agents for specific parameters of immune competence as well as the overall clinical state. Pre-clinical animal studies and in vitro studies on mechanisms of action with immunopotentiators, immunomodulators, immunoadjuvants and other pharmacological agents active on cells participating in immune or allergic responses. Pharmacological compounds, microbial products and toxicological agents that affect the lymphoid system, and their mechanisms of action. Agents that activate genes or modify transcription and translation within the immune response. Substances activated, generated, or released through immunologic or related pathways that are pharmacologically active. Production, function and regulation of cytokines and their receptors. Classical pharmacological studies on the effects of chemokines and bioactive factors released during immunological reactions. Studies on the nature and function of drug and hormone receptors on lymphocytes and other cells in the immune system. Studies of cell-derived or humoral factors that modify the immune system causing cytotoxicity, inducing antibody production and mediating inflammatory responses. The development of immunologically based assays and their application to disease, including assays for drugs, hormones, cyclic nucleotides, tumor antigens, etc.

由爱思唯尔科学出版。ISSN: 1567 - 5769。国际免疫药理学和免疫药理学杂志的合并。国际免疫药理学是发表有关免疫学、药理学、细胞因子生物学、免疫治疗、免疫病理学和免疫毒理学交叉领域的原始研究论文的主要工具。也欢迎评论包含这些主题的文章。适宜提交的研究材料包括:采用任何类型免疫治疗的临床研究，包括使用:细菌和化学制剂;胸腺激素、干扰素、淋巴因子等，用于移植和癌症、免疫缺陷、慢性感染和过敏、炎症或自身免疫性疾病等。研究这些药物对特定免疫功能参数的作用机制以及整体临床状态。临床前动物研究和体外研究免疫增强剂、免疫调节剂、免疫佐剂和其他药物对参与免疫或过敏反应的细胞的作用机制。影响淋巴系统的药理化合物、微生物制品和毒理学制剂及其作用机制。在免疫反应中激活基因或改变转录和翻译的物质。通过具有药理活性的免疫或相关途径激活、产生或释放的物质。细胞因子及其受体的产生、功能和调控。经典药理学研究在免疫反应中释放的趋化因子和生物活性因子的影响。免疫系统中淋巴细胞和其他细胞上药物和激素受体的性质和功能的研究。细胞源性或体液性因子的研究，这些因子修饰免疫系统，导致细胞毒性、诱导抗体产生和介导炎症反应。免疫学检测方法的发展及其在疾病中的应用，包括药物、激素、环核苷酸、肿瘤抗原等的检测。